Nicotinamide (nicotinamide; niacinamide), also known as nicotinamide, is an amide compound of niacin. [1] White crystalline powder; odorless or almost odorless, bitter; slightly hygroscopic. Soluble in water or ethanol, soluble in glycerol. Clinically, it is mainly used to prevent and treat pellagra, stomatitis, glossitis, sick sinus syndrome, atrioventricular block and other problems.

Physicochemical properties

Properties: White needle crystal or crystalline powder, odorless or slightly odorous, slightly bitter taste.

Density (g/mL, 25℃): 1.40

Melting point (°C): 128-131

Boiling point (°C, normal pressure): 257.7

Auto-ignition point or ignition temperature (°C): 480

Solubility: 1g of this product is soluble in 1mL of water, 1.5mL of alcohol and 10mL of glycerol, but insoluble in ether.

Application

1. Biochemical research; nutrient components of tissue culture medium; clinical drugs are vitamin B group, which is used to prevent and treat pellagra, stomatitis, glossitis and other diseases.

2. It is an essential nutrient for mammals. The water solubility is better than that of niacin, but it is easy to form a complex with vitamin C and agglomerate. The dosage is 30mg/kg.

3. Niacinamide and niacin can be used in most situations, and niacin also produces niacinamide in animals. The lack of niacinamide in the body can cause pellagra, so this product can prevent pellagra. Plays a role in protein and sugar metabolism, improving human and animal nutrition. It can be used as a nutritional additive in cosmetics. In addition, it is also used in medicine, food and feed additives.

• Storage method

1. Store in a cool, dry and well-ventilated warehouse. Keep away from fire and heat sources. Keep container tightly closed.

2. It should be stored separately from the oxidant, and should not be mixed. Equipped with the appropriate variety and quantity of fire equipment. Storage areas should be equipped with emergency release equipment and suitable containment materials.